77469-98-8

Basic information

• Product Name: PiMobendan (hydrochloride)
• Synonyms: PiMobendan (hydrochloride);4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone monohydrochloride
• CAS NO: 77469-98-8
• Molecular Formula: C₁₉H₁₈N₄O₂*ClH
• Molecular Weight: 370.83276
• Mol File: 77469-98-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 311°(dec)
• Appearance: /
• CAS DataBase Reference: PiMobendan (hydrochloride)(CAS DataBase Reference)
• NIST Chemistry Reference: PiMobendan (hydrochloride)(77469-98-8)
• EPA Substance Registry System: PiMobendan (hydrochloride)(77469-98-8)

Safety Data

• Hazardous Substances Data: 77469-98-8(Hazardous Substances Data)

Usage

General Description

Pimobendan hydrochloride is a positive inotropic and vasodilator drug used in veterinary medicine to treat congestive heart failure in dogs. It works by increasing the strength of the heart's contractions, which improves the heart's ability to pump blood and oxygen to the body. Additionally, pimobendan helps relax the blood vessels, reducing the heart's workload and improving blood flow. It is often prescribed in combination with other medications, such as diuretics and angiotensin-converting enzyme inhibitors, to manage heart failure and improve the quality of life for dogs with cardiac disease. Pimobendan hydrochloride is generally well-tolerated, although side effects may include decreased appetite, vomiting, or diarrhea. Close monitoring and regular veterinary check-ups are recommended for dogs receiving this medication.

Upstream product

• 118428-37-8 pimobendan 

Relevant articles and documents

Process for preparation of pimobendan hydrochloride

The present invention refers to the process for preparation of pimobendan hydrochloride, to a crystalline form of pimobendan hydrochloride, and to pharmaceutical compositions comprising it.