77472-98-1 Usage
Description
Pipequaline is a partial agonist of central benzodiazepine receptors (Ki = 78 nM in a radioligand binding assay). In mice, pipequaline enhances the effects of diazepam , further reducing foot shock-induced fighting behavior and the number of maximal electroshock-induced seizures and potentiating the muscle relaxant and hypnotic effects. Pipequaline also increases drinking in the Vogel punished drinking task indicating anxiolytic-like activity that can be reversed by the benzodiazepine receptor antagonist flumazenil .
Check Digit Verification of cas no
The CAS Registry Mumber 77472-98-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,4,7 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 77472-98:
(7*7)+(6*7)+(5*4)+(4*7)+(3*2)+(2*9)+(1*8)=171
171 % 10 = 1
So 77472-98-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H24N2/c1-2-6-18(7-3-1)22-16-19(11-10-17-12-14-23-15-13-17)20-8-4-5-9-21(20)24-22/h1-9,16-17,23H,10-15H2
77472-98-1Relevant articles and documents
2-(4-Piperidyl)-1-(4-quinolyl)-ethanones and ethanes
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, (2008/06/13)
Compounds, useful as medicaments, of the formula: STR1 in which R is hydrogen, alkyl, alkenyl or arylalkyl, R1 is hydrogen, alkyl or alkenyl, R2 is hydrogen, alkyl, arylalkyl, phenyl, pyridyl, thienyl or substituted phenyl, X is hydr
