77486-52-3Relevant academic research and scientific papers
REGIOSPECIFIC ALLYLATION OF SULFUR SUBSTITUTED ACTIVE METHYLENE COMPOUNDS WITH ALLYLIC BROMIDES
Ono, Noboru,Miyake, Hideyoshi,Tanabe, Yo,Tanaka, Kazuhiko,Kaji, Aritsune
, p. 1365 - 1368 (2007/10/02)
Allylation of sulfur substituted active methylene compounds such as RSCH2Y with allylic bromides in the presence of bases gives a mixture of the SN2-product and the apparent SN2'-product.The former product is selectively obtained in alkylation in a nonpolar solvent.Synthetic utility of this regiospecific allylation is demonstrated in the simple synthesis of pellitorine.
