77511-23-0Relevant academic research and scientific papers
ONE-POT CYCLIZATION OF A PEPTIDE BY THE USE OF (5-NITROPYRIDYL)DIPHENYL PHOSPHINATE: THE SYNTHESIS OF CYCLIC DECAPEPTIDE GRAMICIDIN S
Mukaiyama, Teruaki,Kamekawa, Kenichi,Watanabe, Yutaka
, p. 1367 - 1370 (2007/10/02)
One-pot synthesis of gramicidin S, cyclic decapeptide, was successfully achieved by treatment of the corresponding linear decapeptide with (5-nitropyridyl)diphenyl phosphinate, a new condensing reagent, in pyridine.Similarly, the phosphinic ester can be successfully employed in the Young test as well as syntheses of dipeptides.
