77516-86-0Relevant academic research and scientific papers
Direct anomeric O-arylation and O-hetarylation of glucose electron deficient aromatic and hetaromatic compounds in aryl and hetaryl glycoside synthesis
Huchel, Ursula,Schmidt, Christoph,Schmidt, Richard R.
, p. 9457 - 9460 (2007/10/02)
Anomeric O-arylation and O-hctarylation of tetra-O-bcnzyl-, tetra-O-acctyl-, and O-unprotected glucose (1a-c) can be directly performed with electron dcficienl aromatic and hctcroaromatic systems having fluoro- (2A-2F) or phenylsulfonyl (3B, 3G-3K), respectively, as leaving groups. The reactions were carried out in DMF as solvent at room temperature with NaH as the base; they led in the products 4 to an exchange of the leaving group by the glucopyranosyloxy moicly; mainly β-products were obtained.
The use of the 2,4-dinitrophenyl group in sugar chemistry re-examined
Koeners, H. J.,Kok, A. J. de,Romers, C.,Boom, J. H. van
, p. 355 - 362 (2007/10/02)
The use of the tertiary base 1,4-diazabicyclooctane, together with 1-fluoro-2,4-dinitrobenzene in the solvent DMF, proved to be an efficient method for the introduction of the 2,4-dinitrophenyl (DNP) group at different positions, including the anom
