77521-40-5

Basic information

• Product Name: (R)-2-[(2R)-Decahydro-8aβ-hydroxy-4aα-methyl-8-methylenenaphthalen-2-yl]-1,2-propanediol
• Synonyms: (R)-2-[(2R)-Decahydro-8aβ-hydroxy-4aα-methyl-8-methylenenaphthalen-2-yl]-1,2-propanediol;Kudtriol
• CAS NO: 77521-40-5
• Molecular Formula: C15H26O3
• Molecular Weight: 254.36514
• Mol File: 77521-40-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-2-[(2R)-Decahydro-8aβ-hydroxy-4aα-methyl-8-methylenenaphthalen-2-yl]-1,2-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-[(2R)-Decahydro-8aβ-hydroxy-4aα-methyl-8-methylenenaphthalen-2-yl]-1,2-propanediol(77521-40-5)
• EPA Substance Registry System: (R)-2-[(2R)-Decahydro-8aβ-hydroxy-4aα-methyl-8-methylenenaphthalen-2-yl]-1,2-propanediol(77521-40-5)

Safety Data

• Hazardous Substances Data: 77521-40-5(Hazardous Substances Data)

Upstream product

• 122421-99-2 11-hydroxyeudesm-4-en-12-al 
• 122421-92-5 methyl (11S)-eudesm-4-en-12-oate 
• 77521-56-3 eudesm-4-ene-11,12-diol 
• 122421-98-1 (11S)-eudesm-4-en-12-al 
• 117030-00-9 (11S)-eudesm-4-en-12-ol 
• 18172-87-7 methyl (11S)-3-oxo-eudesm-4-en-13-oate 
• 3466-64-6 (+)-2-(1,2,3,4,4a,5,6,7-octahydro-4a,8-dimethyl-7-oxo-2-naphthyl)-propionic acid 
• 122442-38-0 methyl (11S)-3,3-ethylenedithioeudesm-4-en-12-oate 
• 288269-08-9 4,5-oxidoselina-11-ene 
• 17627-30-4 α-cyperene 
• 473-08-5 eudesma-4,11-dien-3-one 
• 119967-73-6 (+)-5α-hydroxy-β-selinene 
• 122421-93-6 (R)-2-((2R,4aR,8aR)-8a-Hydroperoxy-4a-methyl-8-methylene-decahydro-naphthalen-2-yl)-propane-1,2-diol 

Relevant articles and documents

APPROACH TO THE SYNTHESIS OF SIDE-CHAIN EUDESMANEDIOLS: SYNTHESIS OF KUDTRIOL FROM 1-(α)-SANTONIN

The synthesis of an eudesmanic alcohol, kudtriol (1), is described along with its 11-deoxy analogue (19) starting from 1-(α)-santonin in ten steps.The known intermediate methyl (11S)-3-oxoeudesm-4-en-12-oate (5b) was taken through the new intermediates methyl (11S)-eudesm-4-en-12-oate (6), (11S)-eudesm-4-en-12-al (17), 11-hydroxyeudesm-4-en-12-al (18), and eudesm-4-ene-11,12-diol (8).The consstruction of side-chain diol moiety in the last mentioned intermediate was achieved by the application of Vedejs' enolate hydroxylation on (17).The sensitized photo-oxygenation cum reduction sequence transformed the ene diol (8) into the title compound (1).A similar sequence on (11S)-eudesm-4-en-12-ol (16) resulted in 11-deoxykudtriol (19).

Eudesmane alcohols from jasonia glutinosa

Three new sesquiterpene alcohols have been isolated from Jasonia glutinosa. Their structures were elucidated by spectroscopic methods and chemical correlations as (-)-[11R]-4α,14-epoxyeudesm-11,12-diol, (-)-[11R]-eudesm-4(14)-en-5β,11,12-triol and (+)-[11R]-eudesm-4(14)-en-5α,11,12-triol and they are called α-epoxy kudtdiol, 5-epi-kudtriol and kudtriol respectively.