77528-71-3

Basic information

• Product Name: 2-Methyl-6-tosyloxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole
• CAS NO: 77528-71-3
• Molecular Weight: 337.464
• Mol File: 77528-71-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Methyl-6-tosyloxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-6-tosyloxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole(77528-71-3)
• EPA Substance Registry System: 2-Methyl-6-tosyloxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole(77528-71-3)

Safety Data

• Hazardous Substances Data: 77528-71-3(Hazardous Substances Data)

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 39086-05-0 ethyl 3-bromo-4-oxocyclohexanecarboxylate 
• 103057-51-8 hypochlorous acid 4-methylbenzene sulfonic anhydride 
• 77528-70-2 2-Methyl-6-hydroxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole 
• 77528-69-9 2-Methyl-6-ethoxycarbonyl-4,5,6,7-tetrahydrobenzo[d]thiazole 
• 3618-04-0 4-hydroxycyclohexyl carboxylic acid ethyl ester 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 

Relevant articles and documents

Synthesis of aminoiderivatives of 4,5,6,7-tetrahydro-benzothiazole. II. 4, 5 and 6-aminomethyl derivatives with cardiovascular activity

The ethyl esters of 4,5,6,7-tetrahdyro-benzothiazolyl-4 carboxylic acids were synthesized from corresponding ethyl 1-oxo-2 bromo-cyclohexane-carboxylates. Their reduction to alcohols, which were then transformed into tosylates, leads to the aminomethyl derivatives. These derivatives are practically devoid of antihistaminic H2 and dopaminergic activities but have interesting cardiovascular properties.