775284-56-5Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of triazolopiperazine-based β-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors
Kowalchick, Jennifer E.,Leiting, Barbara,Pryor, KellyAnn D.,Marsilio, Frank,Wu, Joseph K.,He, Huaibing,Lyons, Kathryn A.,Eiermann, George J.,Petrov, Aleksandr,Scapin, Giovanna,Patel, Reshma A.,Thornberry, Nancy A.,Weber, Ann E.,Kim, Dooseop
, p. 5934 - 5939 (2008/09/20)
Various β-amino amides containing triazolopiperazine heterocycles have been prepared and evaluated as potent, selective, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. These compounds display excellent oral bioavailability and good overall phar
