77530-02-0 Usage
Uses
Used in Pharmaceutical Industry:
Uridine, 5-(2-bromoethenyl)-2'-deoxy-, (Z)is used as a neuroprotective and neuroregenerative agent for the treatment of neurodegenerative diseases and traumatic brain injuries. Its enhanced properties make it a promising candidate for developing new therapeutic approaches to combat these conditions.
Used in Cognitive Function and Memory Enhancement:
Uridine, 5-(2-bromoethenyl)-2'-deoxy-, (Z)is used as a cognitive enhancer to improve memory and cognitive function. Its potential in this area is currently being studied, and further research is needed to fully understand its mechanisms and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 77530-02-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,3 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 77530-02:
(7*7)+(6*7)+(5*5)+(4*3)+(3*0)+(2*0)+(1*2)=130
130 % 10 = 0
So 77530-02-0 is a valid CAS Registry Number.
77530-02-0Relevant academic research and scientific papers
Liang, Yong,Pitteloud, Jean-Philippe,Wnuk, Stanislaw F.
, p. 5761 - 5767 (2013)
A stereoselective radical-mediated hydrogermylation of the protected 5-ethynyluracil nucleosides with trialkyl-, triaryl,- or tris(trimethylsilyl) germanes gave (Z)-5-(2-germylvinyl)uridine, 2′-deoxyuridine, or ara-uridine as major products. Reaction of the β-triphenylgermyl vinyl radical intermediate with oxygen and fragmentation of the resulting peroxyradical provided also 5-[2-(triphenylgermyl)acetyl]pyrimidine nucleosides in low to moderate yields. Thermal isomerization of the latter in MeOH occurred via a four-centered activated complex, and subsequent hydrolysis of the resulting O-germyl substituted enol yielded 5-acetyluracil nucleosides in quantitative yield.
