775307-82-9

Upstream product

• 100-44-7 benzyl chloride 
• 87318-96-5 (4S)-4-((2R)-2-hydroxypent-4-enyl)-2,2-dimethyl-1,3-dioxolane 
• 775307-76-1 tert-Butyl-[(1S,3R)-3-(2-methoxy-ethoxymethoxy)-1-prop-2-ynyl-hex-5-enyloxy]-diphenyl-silane 
• 775307-78-3 (4R,6S)-6-(tert-Butyl-diphenyl-silanyloxy)-non-1-en-8-yn-4-ol 
• 775307-59-0 2,2-Dimethyl-propionic acid (2S,4R)-2-methanesulfonyloxy-4-(2-methoxy-ethoxymethoxy)-hept-6-enyl ester 
• 775307-57-8 2,2-Dimethyl-propionic acid (2S,4R)-2-hydroxy-4-(2-methoxy-ethoxymethoxy)-hept-6-enyl ester 
• 775307-63-6 (4S,6R)-6-(2-Methoxy-ethoxymethoxy)-non-8-en-1-yn-4-ol 
• 775307-53-4 (S)-4-[(R)-2-(2-Methoxy-ethoxymethoxy)-pent-4-enyl]-2,2-dimethyl-[1,3]dioxolane 
• 775307-55-6 (2S,4R)-4-(2-Methoxy-ethoxymethoxy)-hept-6-ene-1,2-diol 
• 775306-99-5 (R)-2-[(R)-2-(2-Methoxy-ethoxymethoxy)-pent-4-enyl]-oxirane 
• 775307-80-7 Benzoic acid (1R,3S)-1-allyl-3-(tert-butyl-diphenyl-silanyloxy)-hex-5-ynyl ester 

Downstream Products

• 775307-29-4 Benzoic acid (1R,3S)-1-(2-hydroxy-ethyl)-3-(4-methoxy-benzyloxy)-hex-5-ynyl ester 
• 775307-84-1 Benzoic acid (1R,3S)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-hydroxy-hex-5-ynyl ester 
• 775307-86-3 benzoic acid 3-(tert-butyl-dimethyl-silanyloxy)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-hex-5-ynyl ester 
• 775307-97-6 Benzoic acid (1R,3S)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-(4-methoxy-benzyloxy)-hex-5-ynyl ester 
• 775307-31-8 benzoic acid 3-(tert-butyl-dimethyl-silanyloxy)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6-iodo-hex-5-enyl ester 
• 775307-33-0 Benzoic acid (5E,12E)-(1R,3S,9R,10R)-3-(tert-butyl-dimethyl-silanyloxy)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-14-hydroxy-9-(4-methoxy-benzyloxy)-10-methyl-tetradeca-5,12-dien-7-ynyl ester 

Relevant academic research and scientific papers

Synthetic studies aimed at (-)-cochleamycin A. Evaluation of late-stage macrocyclization alternatives

An efficient route to the fully functionalized ABC ring systems of the unnatural enantiomer of cochleamycin A was developed. L-(-)-Malic and L-(-)-ascorbic acids served well as starting materials for the two building blocks used to construct an (E,Z,E)-1,