775320-49-5Relevant academic research and scientific papers
Peptide deformylase inhibitors with retro-amide scaffold: Synthesis and structure-activity relationships
Lee, Seung Kyu,Choi, Kwang Hyun,Lee, Sang Jae,Suh, Se Won,Kim, B. Moon,Lee, Bong Jin
supporting information; experimental part, p. 4317 - 4319 (2010/10/03)
Peptide deformylase (PDF) is a metalloprotease catalyzing the removal of a formyl group from newly synthesized proteins. Thus inhibition of PDF activity is considered to be one of the most effective antibiotic strategies. Reported herein are the synthesis
DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME
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Page 32-33, (2008/06/13)
Provided are a novel compound useful for a deformylase inhibitor with excellent antibacterial activity or a pharmaceutically acceptable salt thereof, a process for preparing the same, and an antibacterial composition including the same as an active ingred
