77534-15-7Relevant academic research and scientific papers
2-Amino-3-(alkylthiobenzoyl)-phenylacetic acids
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, (2008/06/13)
Novel 2-amino-3-(alkylthiobenzoyl)phenylacetic acids, esters and metal salts have the formula: STR1 wherein R is hydrogen or lower alkyl, R1 is hydrogen, lower alkyl or pharmaceutically acceptable metal cation, R2 is hydrogen, haloge
Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogues
Walsh,Moran,Shamblee,Uwaydah,Welstead Jr.,Sancilio,Dannenburg
, p. 1379 - 1388 (2007/10/02)
A series of substituted derivatives of 2-amino-3-benzoylphenylacetic acid (amfenac) has been synthesized and evaluated for antiinflammatory, analgesic, and cyclooxygenase inhibiting activity. Several derivatives including 4'-chloro, 4'-bromo and 5-chloro, 4'-bromo were more potent than indomethacin in these assays.
