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Usage

Uses

Used in Pharmaceutical Industry:
3-Cyano-4-fluorophenylboronic acid, pinacol ester is used as a building block for the synthesis of various pharmaceuticals. Its ability to participate in palladium-catalyzed cross-coupling reactions allows for the creation of diverse and complex molecular structures, contributing to the development of new and effective drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Cyano-4-fluorophenylboronic acid, pinacol ester serves as a key intermediate in the synthesis of agrochemicals. Its versatility in organic synthesis enables the production of a variety of compounds with potential applications in crop protection and pest control.
Used in Organic Synthesis:
3-Cyano-4-fluorophenylboronic acid, pinacol ester is used as a versatile reagent in organic synthesis. Its pinacol ester functionality provides stability and increased solubility, making it an ideal starting material for the preparation of various organic compounds. 3-CYANO-4-FLUOROPHENYLBORONIC ACID, PINACOL ESTER can be employed in the synthesis of a wide range of molecules, including those with potential applications in materials science, chemical research, and other specialized fields.
Used in Drug Discovery and Development:
3-Cyano-4-fluorophenylboronic acid, pinacol ester is utilized as a valuable tool in drug discovery and development. Its ability to participate in palladium-catalyzed cross-coupling reactions allows for the creation of novel and complex molecular structures with potential therapeutic properties. 3-CYANO-4-FLUOROPHENYLBORONIC ACID, PINACOL ESTER plays a crucial role in the design and synthesis of new drug candidates, contributing to the advancement of pharmaceutical research.

InChI:InChI=1/C13H15BFNO2/c1-12(2)13(3,4)18-14(17-12)10-5-6-11(15)9(7-10)8-16/h5-7H,1-4H3

Upstream product

• 179897-89-3 5-Bromo-2-fluoro-benzonitrile 
• 73183-34-3 bis(pinacol)diborane 
• 351003-36-6 2-fluoro-5-iodobenzonitrile 

Downstream Products

• 1351502-30-1 2-pyrrolidin-1-yl-5-(4,4,5, 5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile 
• 1356225-62-1 pyrrolidine-1-carboxylic acid-{3-[4-(3-cyano-4-pyrrolidin-1-ylphenyl)pyrimidin-2-ylamino]phenyl}amide 
• 1356226-84-0 5-(2-chloro-pyrimidin-4-yl)-2-pyrrolidin-1-yl-benzonitrile 
• 1356225-22-3 DMX-A 

Relevant academic research and scientific papers

COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

The present invention relates to a compound represented by chemical formula 1 and to an organic light-emitting device comprising the same, wherein the compound is used in the organic light-emitting device to lower driving voltage and improve light efficie

COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

The present specification provides a compound of Formula 1 and an organic light emitting device including the same.

Triggering Thermally Activated Delayed Fluorescence by Managing the Heteroatom in Donor Scaffolds: Intriguing Photophysical and Electroluminescence Properties

Establishment of the structure–property relationships of thermally activated delayed fluorescence (TADF) materials has become a significant quest for the scientific community. Herein, two new donors, 10H-benzofuro[3,2-b]indole (BFI) and 10H-benzo[4,5]thie

Radical Metal-Free Borylation of Aryl Iodides

A simple metal-free borylation of aryl iodides mediated by a fluoride sp 2 -sp 3 diboron adduct is described. The reaction conditions are compatible with various functional groups. Electronic effects of substituents do not affect the borylation while steric hindrance does. The reaction proceeds via a radical mechanism in which pyridine serves to stabilize the boryl radicals, generated in situ.

TBK/IKK INHIBITOR COMPOUNDS AND USES THEREOF

The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as TBK/IKKε inhibitors.

CATHEPSIN C INHIBITORS

Disclosed are 3-aminopyrrolidines of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.

SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.

Microwave-assisted preparation of aryltetrazoleboronate esters

(Chemical Equation Presented) The addition of azido trimethylsilane to arylnitrileboronate esters is shown to proceed rapidly in dimethoxyethane to give aryltetrazoleboronate esters in moderate to good yields, with dibutyltin oxide as catalyst.