775354-25-1

Basic information

• Product Name: (R)-3-((R)-3-tert-Butoxycarbonylamino-4-phenyl-butyryl)-thiazolidine-4-carboxylic acid
• CAS NO: 775354-25-1
• Molecular Weight: 394.492
• Mol File: 775354-25-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-((R)-3-tert-Butoxycarbonylamino-4-phenyl-butyryl)-thiazolidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-((R)-3-tert-Butoxycarbonylamino-4-phenyl-butyryl)-thiazolidine-4-carboxylic acid(775354-25-1)
• EPA Substance Registry System: (R)-3-((R)-3-tert-Butoxycarbonylamino-4-phenyl-butyryl)-thiazolidine-4-carboxylic acid(775354-25-1)

Safety Data

• Hazardous Substances Data: 775354-25-1(Hazardous Substances Data)

Upstream product

• 101555-61-7 (R)-3-t-butoxycarbonylamino-4-phenylbutyric acid 

Relevant articles and documents

Potent and selective proline derived dipeptidyl peptidase IV inhibitors

In-house screening of the Merck sample collection identified proline derived homophenylalanine 3 as a DPP-IV inhibitor with modest potency (DPP-IV IC50 = 1.9 μM). Optimization of 3 led to compound 37, which is among the most potent and selectiv