7754-77-0Relevant academic research and scientific papers
An unexpected ring contraction of two nitroaryl pro-drugs: conversion of N-(nitroaryl)-3-chloropiperidine derivatives into N-(nitroaryl)-2-chloromethylpyrrolidines
Burke, Philip J.,Wong, Lai Chun,Clegg, William,Harrington, Ross W.,Jenkins, Terence C.,Knox, Richard J.,Meikle, Ian T.,Stanforth, Stephen P.
body text, p. 3918 - 3921 (2010/08/20)
Treatment of the N-nitroaryl-3-hydroxypiperidine derivatives 12 and 13 with thionyl chloride afforded the corresponding N-aryl-2-chloromethylpyrrolidines 5 and 15 via a ring-contraction process involving an intermediate aziridinium ion.
Synthesis of novel tricyclic oxazolidinones by a tandem SN2 and SNAr reaction: SAR studies on conformationally constrained analogues of Linezolid
Selvakumar,Yadi Reddy,Sunil Kumar,Khera, Manoj Kumar,Srinivas,Sitaram Kumar,Das, Jagattaran,Iqbal, Javed,Trehan, Sanjay
, p. 4416 - 4419 (2007/10/03)
A series of conformationally constrained analogues of Linezolid were synthesised by employing a tandem SN2 and SNAr reaction as the key step and tested for antibacterial activity. While the hexahydroazolo-quinoxaline compounds were inactive, th
Observation of O→N type smiles rearrangement in certain alkyl aryl nitro compounds
Selvakumar, Natesan,Srinivas, Deekonda,Azhagan, Azagarsamy Malar
, p. 2421 - 2425 (2007/10/03)
Smiles rearrangements on some alkyl aryl nitro compounds having NH2 group as the nucleophile and oxygen as the leaving group are reported.
