7754-77-0

Basic information

• Product Name: 2-Pyrrolidinemethanol, 1-(2,4-dinitrophenyl)-, (S)-
• CAS NO: 7754-77-0
• Molecular Formula: C11H13N3O5
• Molecular Weight: 267.241
• Mol File: 7754-77-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinemethanol, 1-(2,4-dinitrophenyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinemethanol, 1-(2,4-dinitrophenyl)-, (S)-(7754-77-0)
• EPA Substance Registry System: 2-Pyrrolidinemethanol, 1-(2,4-dinitrophenyl)-, (S)-(7754-77-0)

Safety Data

• Hazardous Substances Data: 7754-77-0(Hazardous Substances Data)

Upstream product

• 70-34-8 2,4-Dinitrofluorobenzene 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 509151-90-0 1-[(S)-2-(2,4-Dinitro-phenoxymethyl)-pyrrolidin-1-yl]-ethanone 
• 66158-68-7 (S)-1-(2-(hydroxymethyl) pyrrolidin-1-yl)ethanone 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 909019-98-3 [3-Benzyloxycarbonylamino-4-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-phenyl]-carbamic acid benzyl ester 
• 1240310-06-8 C₁₁H₁₂ClN₃O₄ 
• 1240310-05-7 C₁₁H₁₂ClN₃O₄ 
• 909019-99-4 [3-Benzyloxycarbonylamino-4-((S)-2-bromomethyl-pyrrolidin-1-yl)-phenyl]-carbamic acid benzyl ester 

Relevant articles and documents

An unexpected ring contraction of two nitroaryl pro-drugs: conversion of N-(nitroaryl)-3-chloropiperidine derivatives into N-(nitroaryl)-2-chloromethylpyrrolidines

Treatment of the N-nitroaryl-3-hydroxypiperidine derivatives 12 and 13 with thionyl chloride afforded the corresponding N-aryl-2-chloromethylpyrrolidines 5 and 15 via a ring-contraction process involving an intermediate aziridinium ion.

Observation of O→N type smiles rearrangement in certain alkyl aryl nitro compounds

Smiles rearrangements on some alkyl aryl nitro compounds having NH2 group as the nucleophile and oxygen as the leaving group are reported.