77540-93-3

Upstream product

• 77540-92-2 Benzoic acid (1S,2S,3R,4S)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4-(tetrahydro-pyran-2-yloxy)-cyclopentyl ester 
• 77540-89-7 1-[(1S,2R,3S,5R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-ethane-1,2-diol 
• 77540-90-0 (1S,2R,3S,4R)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4-(tetrahydro-pyran-2-yloxy)-cyclopentanol 
• 58707-51-0 (3aS,4R,5S,6aR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one 
• 77540-88-6 (3aR,4R,5S,6aR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-3-hydroxy-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one 

Downstream Products

• 77540-94-4 Benzoic acid (1S,2S,3S,4S)-2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3-((E)-3-oxo-oct-1-enyl)-4-(tetrahydro-pyran-2-yloxy)-cyclopentyl ester 
• 77540-98-8 Benzoic acid (1S,2S,3S,4S)-4-hydroxy-3-((E)-3-hydroxy-oct-1-enyl)-2-((Z)-6-methoxycarbonyl-hex-1-enyl)-cyclopentyl ester 
• 77540-97-7 Benzoic acid (1R,2R,3R,4R)-2-((Z)-6-carboxy-hex-1-enyl)-4-hydroxy-3-((E)-3-hydroxy-oct-1-enyl)-cyclopentyl ester 
• 77540-96-6 Benzoic acid (1S,2S,3S,4S)-2-formyl-4-hydroxy-3-((E)-3-hydroxy-oct-1-enyl)-cyclopentyl ester 
• 77540-95-5 Benzoic acid (1S,2R,3S,4S)-2-(1,2-dihydroxy-ethyl)-4-hydroxy-3-((E)-3-hydroxy-oct-1-enyl)-cyclopentyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF THE SULFUR ANALOG OF Δ6-PGI1

A synthesis of the sulfur analog of Δ6-PGI1 with potent inhibitory activity in platelet aggregation is described.The synthesis starting from the suitably protected Corey lactone includes the hydroxylation of the lactone and the novel