775562-81-7Relevant academic research and scientific papers
A novel trifunctional organocatalyst for the asymmetric aldol reaction: A facile enantioselective synthesis of β-hydroxyketones
Subba Reddy,Bhavani,Raju,Yadav
, p. 881 - 886 (2011)
A new l-prolinamide trifunctional catalyst has been developed for the enantioselective aldol reaction of various aromatic and aliphatic aldehydes with acetone. This method provides high yields of β-hydroxyketones (up to 90%) with good enantioselectivity (up to 92%) at a low catalyst loading (10 mol %).
