77557-01-8 Usage
Uses
Used in Pharmaceutical Synthesis:
2H-Benzimidazol-2-one,1,3-dihydro-1-propyl-(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be incorporated into the design and development of new drugs, enhancing their therapeutic properties and effectiveness.
Used in Medicinal Chemistry Research:
As a building block in medicinal chemistry, 2H-Benzimidazol-2-one,1,3-dihydro-1-propyl-(9CI) is employed for the exploration of its potential biological activities. Researchers use 2H-Benzimidazol-2-one,1,3-dihydro-1-propyl-(9CI) to investigate its interactions with biological targets and its potential role in the treatment of various diseases.
Used in Drug Development:
Due to its unique structure and properties, 2H-Benzimidazol-2-one,1,3-dihydro-1-propyl-(9CI) has potential applications in the development of new drugs and therapeutic agents. Its versatility in chemical synthesis and potential biological activities make it a valuable asset in the creation of innovative treatments for various medical conditions.
Used in Organic Compound Synthesis:
Beyond its pharmaceutical applications, 2H-Benzimidazol-2-one,1,3-dihydro-1-propyl-(9CI) is also utilized in the synthesis of other organic compounds. Its reactivity and structural features contribute to the development of new organic molecules with diverse applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 77557-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,5 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 77557-01:
(7*7)+(6*7)+(5*5)+(4*5)+(3*7)+(2*0)+(1*1)=158
158 % 10 = 8
So 77557-01-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2O/c1-2-7-12-9-6-4-3-5-8(9)11-10(12)13/h3-6H,2,7H2,1H3,(H,11,13)
77557-01-8Relevant academic research and scientific papers
Photocatalytic Intramolecular C-H Amination Using N-Oxyureas as Nitrene Precursors
Ivanovich, Ryan A.,Polat, Dilan E.,Beauchemin, André M.
supporting information, p. 6360 - 6364 (2020/09/02)
Nitrenes are remarkable high-energy chemical species that enable direct C-N bond formation, typically via controlled reactions of metal-stabilized nitrenes. Here, in contrast, the combined use of photocatalysis with careful engineering of the precursor enabled C-H amination forming imidazolidinones and related nitrogen heterocycles from readily accessible hydroxylamine precursors. Preliminary mechanistic results are consistent with the formation of free carbamoyl triplet nitrenes as reactive intermediates.
Some Reactions of 2-(n-Propyl/β-carboxyethyl)-3,1-benzoxazin-4(H)-ones and 2-(n-Propyl/β-carboxyethyl)-4(3H)-quinazolinones
Essawy, A.,El-Hashash, M. A.,El-Gendy, A. M.,Hamad, M. M. M.
, p. 593 - 595 (2007/10/02)
Reaction of 2-(n-propyl/β-carboxyethyl)-3,1-benzoxazin-4-ones (1a,b) with aromatic amines gives 3-aryl-2-(n-propyl/β-carboxyethyl)-4(3H)-quinazolinones (2a-e).Compound 1a reacts with hydrazine hydrate and phenylhydrazine to give 3-amino-2-n-propyl-4(3H)-q
