77586-11-9Relevant academic research and scientific papers
STRUCTURE OF PRODUCTS OF ADDITION OF THIOSEMICARBAZIDES AND THIOSEMICARBAZONES TO ACETYLENEDICARBOXYLIC ACID AND ITS DIMETHYL ESTER
Kauss, V. Ya.,Liepin'sh, E. E.,Kalvin'sh, I. Ya.,Lukevits, E.
, p. 103 - 107 (2007/10/02)
Addition of 1,1-di-, 1,4-di-, and 1,1,4-trisubstituted thiosemicarbazides to acetylenedicarboxylic acid and its dimethyl ester affords 2-hydrazono-4-oxo-1,3-thiazolidine-Δ5,α-acetic acids, while 4-monosubstituted thiosemicarbazides give 2-imino-3-amino-1,3-thiazolidin-4-ones.
Addition Reactions of Heterocyclic Compounds. Part 74. Products from Dimethyl Acetylenedicarboxylate with Thiourea, Thioamide, and Guanidine Derivatives
Acheson, R. Morrin,Wallis, John D.
, p. 415 - 422 (2007/10/02)
Benzimidazole-2-thione with dimethyl acetylenedicarboxylate (DMAD) in acetonitrile gave a fused thiazolidinone derivative, but in methanol a fused thiazinone was obtained.Structures were assigned to adducts from other thioureas by comparison with the 13C n.m.r. spectra for these compounds.A method has been developed for distinguishing between the possible structural types of adducts for guanidine and amidine derivatives with DMAD using 1H and 13C n.m.r. spectroscopy.Products from various thioamides and DMAD were identified from their n.m.r. and other spectra.
