77597-16-1

Upstream product

• 77597-12-7 Hydroxy-{2-oxo-4-[2-(tetrahydro-pyran-2-yloxy)-ethylsulfanylthiocarbonylsulfanyl]-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 77597-10-5 4-<<<<2-<(tetrahydropyran-2-yl)oxy>ethyl>thio>thiocarbonyl>thio>-2-azetidinone 
• 77597-14-9 p-nitrobenzyl 2-<4-<<<<2-<(tetrahydropyran-2-yl)oxy>ethyl>thio>thiocarbonyl>thio>-2-oxo-1-azetidinyl>-2-(triphenylphosphoranylidene)acetate 

Downstream Products

• 77597-20-7 p-nitrobenzyl 2-<4-<<<<2-(tert-butyldimethylsilyloxy)ethyl>thio>thiocarbonyl>thio>-2-oxo-1-azetidinyl>-2-(triphenylphosphoranylidene)acetate 
• 77597-18-3 [2-(2-Acetoxy-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

2-(ALKYLTHIO)PENEM-3-CARBOXYLIC ACIDS. II. CHEMICAL MANIPULATION OF PENEM SIDE CHAINS

The tert-butyldimethylsilyl group was found to be effective for protection of the hydroxyl group in penem synthesis.Manipulation of the side-chain hydroxyl group of base-sensitive penem-3-carboxylates was successfully conducted by means of a displacement