Mafenide acetate, also known as sulfamylon, is a topical antiseptic and carbonic anhydrase inhibitor used primarily for the treatment of second-degree burns and partial-thickness burns. It is a sulfonamide derivative that works by inhibiting the enzyme carbonic anhydrase, which is essential for bacterial growth, and by its direct bactericidal action against a wide range of microorganisms, including gram-positive and gram-negative bacteria, as well as some fungi. Mafenide acetate is particularly effective against Pseudomonas aeruginosa, a common cause of burn wound infections. It is applied as a cream or solution directly to the affected area and helps in reducing the risk of infection and promoting wound healing. However, it is important to note that mafenide acetate can cause metabolic acidosis and should be used with caution in patients with impaired kidney function.
The CAS Registry Mumber 7761-27-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,6 and 1 respectively; the second part has 2 digits, 2 and 7 respectively. Calculate Digit Verification of CAS Registry Number 7761-27: (6*7)+(5*7)+(4*6)+(3*1)+(2*2)+(1*7)=115 115 % 10 = 5 So 7761-27-5 is a valid CAS Registry Number.