77620-53-2

Upstream product

• 2270-40-8 4,15-diacetoxyscirpenol 
• 77620-47-4 4β,15-Diacetoxy-3α-hydroxy-12,13-epoxytrichothec-9-en-8-one 
• 77620-47-4 4β,15-diacetoxy-3α-hydroxyscirpen-8-one 
• 81331-38-6 4β,15-diacetoxy-8-bromoscirpen-3α-ol 
• 2270-40-8 anguidine 
• 36519-25-2 4β,15-diacetoxyscirpene-3α,8β-diol 
• 108947-28-0 4β,15-diacetoxy-3α-(2-tetrahydropyranyloxy)scirpene-8β-ol 

Downstream Products

• 77620-55-4 4β,15-Diacetoxy-12,13-epoxytrichothec-9-en-3,8-dione 
• 77620-55-4 4β,15-diacetoxyscirpene-3,8-dione 
• 77620-47-4 4β,15-diacetoxy-3α-hydroxyscirpen-8-one 
• 77620-58-7 15-acetoxy-4β-(methacryloyloxy)scirpene-3,8-dione 
• 81331-42-2 15-acetoxy-4β-(methacryloyloxy)scirpene-3α,8β-diol 
• 77620-59-8 4β,15-bis(methacryloyloxy)scirpene-3,8-dione 
• 81331-43-3 4β,15-bis(methacryloyloxy)scirpene-3α,8β-diol 
• 36519-25-2 4β,15-diacetoxyscirpene-3α,8α-diol 
• 76348-84-0 15-deacetylneosolaniol 

Relevant academic research and scientific papers

Phytotoxic Compounds Produced by Fusarium equiseti. Part 10. The Preparation and Rearrangement of Diacetylneosolaniol 9β,10β-epoxide

Under conditions where trichothecodiol 9β,10β-epoxide rearranges to an 8α,9α:10β,13-diepoxytrichothecan-12-ol, diacetylneosolaniol 9β,10β-epoxide gives a 9α,15:12,13-diepoxytrichothecan-10β-ol.Some by-products formed during the allylic bromination and allylic oxidation od diacetoxyscirpenol have been identified.One of them is a 3α,11α:12,13-diepoxytrichothecene.

THE FACILE CONVERSION OF T-2 TOXIN AND NEOSOLANIOL INTO ANGUIDINE

T-2 Toxin (5) and neosolaniol (6) are readily converted into anguidine (1) by a procedure where deoxygenation at the C-8 position is achieved, after conversion of the 3-TBDMS ether 7 of neosolaniol (6) to the β-bromide 11 for reduction to the anguidine precursor 12.