77629-14-2Relevant academic research and scientific papers
Highly Stereoselective Route to (E)-Allyl Amines via Vinyltri-n-butylphosphonium Salts (Schweizer Reaction)
Meyers, A. I.,Lawson, Jon P.,Carver, David R.
, p. 3119 - 3123 (2007/10/02)
The reaction of vinyltri-n-butylphosphonium salts, aldehydes, and sodiophthalimide in THF gave good yields of the allylic phthalimides with high E stereoselectivity (75-100percent).The use of the vinyltriphenylphosphonium salts (Schweizer reaction) gave the allyl phthalimide with the Z isomer predominating.A study of the phthalimide cation and the effect of added lithium salt showed some reversal in the olefin geometry but in general the selectivity was only 3:1
