77643-57-3

Upstream product

• 935-02-4 3-Phenyl-2-propynonitrile 
• 100-46-9 benzylamine 
• 37854-15-2 2-bromo-3-phenyl-2-propenenitrile 
• 19521-13-2 α,β-dibromo-β-phenylpropionitrile 

Downstream Products

• 614-16-4 Benzoylacetonitrile 
• 100-46-9 benzylamine 

Relevant academic research and scientific papers

Preparation method of beta-amino acrylonitrile compounds

The invention discloses a preparation method of beta-amino acrylonitrile compounds. Beta-aminocyanoacrylate represented by formula I reacts in a solvent under the action of a catalyst to obtain the beta-aminoacrylonitrile compounds represented by formula II; and in the formulas, R is a C1-C12 alkyl group, a halogenated C1-C12 alkyl group, a C3-C12 cycloalkyl group, a C2-C12 alkenyl group, a C2-C12 alkynyl group, an aryl group, a substituted aryl group, a benzyl group or a substituted benzyl group, and R is hydrogen, halogen, a hydroxyl group, an amino group, a cyano group, a nitro group,a C1-C12 alkyl group or a halogenated C1-C12 alkyl group. The method has the characteristics of good stereoselectivity, high yield, simplicity preparation of the raw material beta-aminocyanoacrylate,and great practical value.

Addition de cyano-2 aziridines a quelques alcynes; obtention de pyrroles

Addition of the α-bromocinnamonitrile to primary amines (Cromwell method) leads to 2-cyano-3-phenyl-N-alkyl-aziridines, but the formation of the isomeric enamines always competes with this reaction.These aziridines, which are potential azomethine-ylids, a