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"Z-Trp-Gly-Gly-Gly-Cys(Trt)-OtBu" is a peptide compound consisting of six amino acids: Z-protected tryptophan (Trp), glycine (Gly), and trityl-protected cysteine (Cys). The sequence is Z-Trp-Gly-Gly-Gly-Cys(Trt), and the terminal cysteine is protected with a trityl group, which is a bulky, electron-rich aryl group that prevents unwanted side reactions. The OtBu group indicates that a tert-butyl group is attached to the peptide, which serves as a protecting group for the carboxylic acid terminus. This specific sequence and protection scheme are used in peptide synthesis to control the reactivity of the peptide and to facilitate its purification and characterization. The compound is of interest in chemical biology and medicinal chemistry, particularly in the study of protein structure and function, as well as in the development of new therapeutics.

77657-07-9

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77657-07-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 77657-07-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,6,5 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77657-07:
(7*7)+(6*7)+(5*6)+(4*5)+(3*7)+(2*0)+(1*7)=169
169 % 10 = 9
So 77657-07-9 is a valid CAS Registry Number.

77657-07-9Downstream Products

77657-07-9Relevant academic research and scientific papers

248. Iodine Oxidation of S-Trityl- and S-Acetamidomethyl-cysteine-peptides Containing Tryptophan: Conditions Leading to the Formation of Tryptophan-2-thioethers

Sieber, Peter,Kamber, Bruno,Riniker, Bernhard,Rittel, Werner

, p. 2358 - 2363 (2007/10/02)

Cystine peptides are conveniently prepared from S-acetamidomethyl- or S-trityl-protected cysteine derivatives by direct oxidation with iodine.Since the reaction proceeds through the formation of sulfenyl iodides, these highly reactive goups may substitute

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