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2-(benzhydryl-(2-hydroxyethyl)amino)ethanol, commonly known as diphenhydramine, is an antihistamine medication that is widely used to alleviate symptoms associated with allergies. It functions by inhibiting the effects of histamine, a chemical responsible for triggering allergic reactions. Diphenhydramine also possesses sedative properties, making it a popular choice for promoting sleep. It is available in multiple forms, such as tablets, capsules, and liquid, and is typically administered on an as-needed basis for allergy relief or as a sleep aid. However, its use should be approached with caution, particularly in older individuals, due to potential side effects like drowsiness and dizziness.

77657-67-1

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77657-67-1 Usage

Uses

Used in Pharmaceutical Industry:
2-(benzhydryl-(2-hydroxyethyl)amino)ethanol is used as an antihistamine for treating [application reason] allergic symptoms such as sneezing, itching, and runny nose. It achieves this by blocking the action of histamine, the substance that causes these symptoms.
Used in Sleep Aid Applications:
In the sleep aid industry, 2-(benzhydryl-(2-hydroxyethyl)amino)ethanol is used as a sedative to help individuals who have difficulty falling asleep or staying asleep, due to its calming and sleep-inducing effects.
Used in Over-the-counter Medications:
2-(benzhydryl-(2-hydroxyethyl)amino)ethanol is used as an active ingredient in over-the-counter allergy and sleep aid medications for its effectiveness in providing quick relief from allergy symptoms and promoting sleep.
Used in Geriatric Care:
In geriatric care, 2-(benzhydryl-(2-hydroxyethyl)amino)ethanol is used with caution as a sleep aid or for allergy relief in older adults, given the potential for increased sensitivity to its sedative effects and the need to monitor for side effects such as drowsiness and dizziness.

Check Digit Verification of cas no

The CAS Registry Mumber 77657-67-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,6,5 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77657-67:
(7*7)+(6*7)+(5*6)+(4*5)+(3*7)+(2*6)+(1*7)=181
181 % 10 = 1
So 77657-67-1 is a valid CAS Registry Number.

77657-67-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[benzhydryl(2-hydroxyethyl)amino]ethanol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77657-67-1 SDS

77657-67-1Downstream Products

77657-67-1Relevant academic research and scientific papers

Aldehydes, tert. Amines or Acetales from Amidacetales and Grignard-Compounds

Walther, H.,Haase, L.,Gross, H.,Costisella, B.,Keitel, I.

, p. 902 - 908 (2007/10/02)

Amidacetales 1 or -mercaptales 9 respectively react with Grignard-agents dependent on molar ratio by exchange of methoxy- or methylthio group via not isolable O,N- or S,N-acetales to the corresponding aldehydes 4 or the tert. amines 3.Starting from bicyclic amidacetales 6 aldehydes or bis-β-hydroxyethylamines 8 are formed.By quarternisation of the amidacetal-nitrogen followed by reaction with Grignard-agents the corresponding O,O-acetales are formed.

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