77657-88-6Relevant academic research and scientific papers
Preparation of thiochromans via thermal cyclization
Jensen,Manczuk,Nelson,Caswell,Fleming
, p. 1527 - 1531 (2000)
Formation of the thiochroman ring system is achieved by a two step synthesis that involves heating 3-thiophenyl-1-propanols or 4-thiophenyl-2-butanols in toluene with catalytic amounts of p-toluenesulfonic acid. The propanols are made by the addition of s
A facile and highly diastereoselective synthesis of cis-2,4- diarylthiochromans
Guha, Chayan,Pal, Rammohan,Mallik, Asok K.
, p. 85 - 94,10 (2020/09/02)
A simple methodology has been developed for diastereoselective synthesis of cis-2,4-diarylthiochromans in three steps starting from chalcones. The methodology involves reduction of the conjugate addition product of thiophenol to chalcones followed by Ambe
Cyclization of 1,3-diaryl-3-phenylsulfanyl-1-propanols to thiochromans with the participation of [1,3]-PhS shift
Skarzewski, Jacek,Zielińska-B?ajet, Mariola,Roszak, Szczepan,Turowska-Tyrk, Ilona
, p. 3621 - 3626 (2007/10/03)
Optically active (3R,1RS)-3-aryl-1-phenyl-3-phenylsulfanyl-1-propanols were easily dehydrated forming mainly rac-cis-2-aryl-4-phenylthiochroman, and rac-cis-4-aryl-2-phenylthiochroman along with the corresponding trans-isomers. The observed reaction outco
Neighboring Group Participation in the Oxidation of Hydroxy Sulfides. Control of the Reaction Courses and Products
Ueno, Yoshio,Miyano, Tadaaki,Okawara, Makoto
, p. 3615 - 3618 (2007/10/02)
Oxidation of the hydroxy sulfides with hexabutyldistannoxane (HBD)-bromine system was studied in order to clarify neighboring group participation during the course of reaction.The oxidation products were found to be highly dependent on
