77670-34-9Relevant academic research and scientific papers
Conjugated addition reactions of nitroalkanes with electrophilic alkenes in aqueous media
Ballini, Roberto,Bosica, Giovanna
, p. 355 - 357 (1998)
The Michael reaction of various nitroalkanes 1 with electrophilic alkenes 2 can be performed in NaOH (0.025-0.1 M), without any organic solvent. In many cases the presence of cetyltrimethylammonium chloride (CTACI), as cationic surfactant, produces better
Use of heterogeneous catalyst KG-60-NEt2 in Michael and Henry reactions involving nitroalkanes
Ballini, Roberto,Bosica, Giovanna,Livi, Damiana,Palmieri, Alessandro,Maggi, Raimondo,Sartori, Giovanni
, p. 2271 - 2273 (2007/10/03)
The N,N-diethylpropylamine supported on amorphous silica (KG-60-NEt2) catalyses the formation of carbon-carbon bonds by nitroalkanes through both the nitroaldol (Henry) and Michael reactions. The catalyst shows general utility with a variety of electrophilic acceptors. Moreover, the catalyst can be reused for two further cycles without loss of the activity.
ORGANIC REACTIONS WITHOUT SOLVENT: MICHAEL ADDITIONS ON AN UNSATURATED SULFONE AND SULFOXIDE
Galons, Herve,Labidalle, Serge,Miocque, Marcel,Ligniere, Beatrice,Bram, Georges
, p. 73 - 78 (2007/10/02)
Solid-liquid phase transfer catalysis in the absence of any solvent efficiently promotes Michael additions of nitro alkanes and of diethyl N-acetylaminomalonate to phenyl vinyl sulfone and to phenyl vinyl sulfoxide.The adduct of the Michael addition to di
Asymmetric Induction in the Michael Reaction by Means of Chiral Phase-transfer Catalysts derived from Cinchona and Ephedra Alkaloids
Colonna, Stefano,Re, Alberto,Wynberg, Hans
, p. 547 - 552 (2007/10/02)
Asymmetric induction in the Michael reaction has been achieved using alkaloidonium salts in a two-phase system with optical yields of up to 36 and 26percent in the addition to αβ-unsaturated ketones of thiols and nitroalkanes respectively.The presence of a hydroxy-group β to the 'onium function is essential to achieve substantial asymmetric syntheses.
