77671-38-6Relevant academic research and scientific papers
4-Aroylimidazol-2-ones and their use as pharmaceuticals
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, (2008/06/13)
Novel 4-aroylimidazol-2-ones of the following general structure which are useful as antihypertensives, cardiotonics, antithrombotics, bronchodilators and uterospasmolytics STR1 wherein Ar is 2-furyl, 2-thienyl or phenyl, the latter of which may optionally
4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
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, (2008/06/13)
1,3-Dihydro-2H-imidazol-2-ones having 5-acyl and 4-(substituted amino)methyl substituents, are useful as cardiotonics, antihypertensives and antithrombotic agents. The compounds are obtained by the reaction of an appropriate amine with a substituted 4-bro
4-Aroyl-1,3-dihydro-2H-imidazol-2-ones, a new class of cardiotonic agents
Schnettler,Dage,Grisar
, p. 1477 - 1481 (2007/10/02)
A series of 4-aroyl-1,3-dihydro-2H-imidazol-2-ones was synthesized and evaluated for pharmacological activity in the anesthetized dog. Most members of this series produced dose-related increases in cardiac contractile force as well as relatively minor inc
4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
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, (2008/06/13)
1,3-Dihydro-2H-imidazol-2-ones having 5-acyl and 4-(4-phenyl-1-piperidinyl)methyl substituents, are useful as cardiotonics, antihypertensives and antithrombotic agents. The compounds are obtained by the reaction of an appropriate substituted piperidine wi
