7768-88-9

Basic information

• Product Name: (10R,13R,17R)-3-Chloro-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-one oxime
• CAS NO: 7768-88-9
• Molecular Weight: 436.121
• Mol File: 7768-88-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (10R,13R,17R)-3-Chloro-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-one oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (10R,13R,17R)-3-Chloro-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-one oxime(7768-88-9)
• EPA Substance Registry System: (10R,13R,17R)-3-Chloro-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-one oxime(7768-88-9)

Safety Data

• Hazardous Substances Data: 7768-88-9(Hazardous Substances Data)

Downstream Products

• 1056-93-5 3β-chloro-5α-cholestan-6-one 
• 86679-08-5 3β-chloro-5α-cholest 6,7-2' methyl oxazole 
• 1056-93-5 (5S,10R,13R,17R)-3-Chloro-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-one 
• 87649-51-2 3β-chloro-6-nitrimino-5α-cholestane 

Relevant articles and documents

Reaction of Nitrosyl Chloride Gas with Unsaturated Steroids

Reaction of nitrosyl chloride gas at 0 deg C with 3,5-cholestadiene (1) provided 3,6β-dinitro-5-chloro-5α-cholest-3-ene (4) and with 3α,5-cyclo-5α-cholestan-6-one (2) afforded 3β-chloro-5-nitro-5α-cholestan-6-one (7) and 3β-chloro-6-nitrato-5-cholestene (8).Similar reaction with 6-hydroxylimino 3α,5-cyclo-5α-cholestane (3) gave 3β,6-dichloro-6-cholestene (10), 3β-chloro-6-nitratoimino-5α-cholestane (11) and 3β,5-dichloro-6-nitroimino-5β-cholestane (12).Compound 12 upon hydrolysis furnished 3β,5-dichloro-5β-cholestan-6-one (14).The structures of these compounds were established on the basis of their spectral properties, and some pertinent chemical transformations.Mechanisms for the formation of some unusual products are discussed.