77692-53-6Relevant academic research and scientific papers
Room temperature aldol reactions using magnetic Fe3O 4@Fe(OH)3 composite microspheres in hydrogen bond catalysis
Niu, Fang,Zhang, Long,Luo, San-Zhong,Song, Wei-Guo
, p. 1109 - 1111 (2010)
Fe3O4@Fe(OH)3 composite microspheres are highly active, environmentally friendly and easy to recycle catalysts for aldol reactions, which are catalyzed by a solid-liquid interfacial hydrogen bond catalyst at room temperature.
Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists
Matthews, Jay M.,McNally, James J.,Connolly, Peter J.,Xia, Mingde,Zhu, Bin,Black, Shawn,Chen, Cailin,Hou, Cuifen,Liang, Yin,Tang, Yuting,Macielag, Mark J.
, p. 5346 - 5349 (2016/10/30)
A series of potent and receptor-selective cannabinoid-1 (CB1) receptor inverse agonists has been discovered. Peripheral selectivity of the compounds was assessed by a mouse tissue distribution study, in which the concentrations of a test compound in both plasma and brain were measured. A number of peripherally selective compounds have been identified through this process. Compound 2p was further evaluated in a 3-week efficacy study in the diet-induced obesity (DIO) mouse model. Beneficial effects on plasma glucose were observed from the compound-treated mice.
Reactions with (Arylmethylene)cycloalkanones. 5. Synthesis of 2-Acetyl-5-aryl-5,6,7,8,9,10-hexahydrocycloheptathiazolopyrimidin-3(2H)-ones of Probable Biological Activity
All, Mohamed I.,Hammam, Abou El-Fotooh G.
, p. 342 - 343 (2007/10/02)
Cycloheptapyrimidine-2-thiones (III) were prepared by heating 2-(arylmethylene)cycloheptanones with thiourea in ethanolic potassium hydroxide.Compounds III reacted with chloroacetic acid in acetic anhydride to yield the title compounds (IV).Compounds I
