777089-62-0Relevant academic research and scientific papers
Conformational constraint in oxazolidinone antibacterials. Part 2: Synthesis and structure-activity studies of oxa-, aza-, and thiabicyclo[3.1.0] hexylphenyl oxazolidinones
Renslo, Adam R.,Gao, Hongwu,Jaishankar, Priyadarshini,Venkatachalam, Revathy,Gomez, Marcela,Blais, Johanne,Huband, Michael,Vara Prasad,Gordeev, Mikhail F.
, p. 1126 - 1129 (2007/10/03)
A new class of oxazolidinone antibacterials incorporating oxygen-, nitrogen-, or sulfur-containing heterobicyclic C-rings is described. The in vitro potency and in vivo efficacy of these conformationally constrained oxazolidinone analogs are discussed.
Synthesis of aza-, oxa-, and thiabicyclo[3.1.0]hexane heterocycles from a common synthetic intermediate
Renslo, Adam R.,Gao, Hongwu,Jaishankar, Priyadarshini,Venkatachalam, Revathy,Gordeev, Mikhail F.
, p. 2627 - 2630 (2007/10/03)
(Chemical Equation Presented) An efficient and stereospecific approach to the synthesis of structurally constrained aza-, oxa-, and thiabicyclo[3.1.0] hexane heterocycles has been achieved through application of the intramolecular cyclopropanation reactio
