777089-64-2

Upstream product

• 777089-59-5 (2E)-3-{4-[((benzyloxy)carbonyl)amino]phenyl}prop-2-enyl diazoacetate 
• 92159-87-0 benzyl (4-bromophenyl)carbamate 
• 71150-68-0 benzyl N-(4-formylphenyl)carbamate 
• 777089-61-9 [4-((1S,2R,3S)-2,3-Bis-hydroxymethyl-cyclopropyl)-phenyl]-carbamic acid benzyl ester 
• 777089-58-4 benzyl 4-[(1E)-3-hydroxyprop-1-enyl]phenylcarbamate 
• 777089-57-3 methyl (2E)-3-(4-{[(benzyloxy)carbonyl]amino}phenyl)acrylate 
• 881012-64-2 Methanesulfonic acid (1S,2S,3R)-2-(4-benzyloxycarbonylamino-phenyl)-3-methanesulfonyloxymethyl-cyclopropylmethyl ester 
• 2393-23-9 4-methoxy-benzylamine 

Downstream Products

• 777089-65-3 N-[((5S)-3-{4-[(1α,5α,6β)-3-(4-methoxybenzyl)-3-azabicyclo[3.1.0]hex-6-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl)methyl]acetamide 

Relevant academic research and scientific papers

Conformational constraint in oxazolidinone antibacterials. Part 2: Synthesis and structure-activity studies of oxa-, aza-, and thiabicyclo[3.1.0] hexylphenyl oxazolidinones

A new class of oxazolidinone antibacterials incorporating oxygen-, nitrogen-, or sulfur-containing heterobicyclic C-rings is described. The in vitro potency and in vivo efficacy of these conformationally constrained oxazolidinone analogs are discussed.

Synthesis of aza-, oxa-, and thiabicyclo[3.1.0]hexane heterocycles from a common synthetic intermediate

(Chemical Equation Presented) An efficient and stereospecific approach to the synthesis of structurally constrained aza-, oxa-, and thiabicyclo[3.1.0] hexane heterocycles has been achieved through application of the intramolecular cyclopropanation reactio