777089-91-5

Upstream product

• 777089-90-4 [(S)-3-((1S,5R,6S)-3,5-Difluoro-4-3-thia-bicyclo[3.1.0]hex-6-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-carbamic acid tert-butyl ester 
• 777090-08-1 (S)-5-Aminomethyl-3-((1S,5R,6S)-3,5-difluoro-4-3-thia-bicyclo[3.1.0]hex-6-yl-phenyl)-oxazolidin-2-one 

Relevant academic research and scientific papers

Conformational constraint in oxazolidinone antibacterials. Part 2: Synthesis and structure-activity studies of oxa-, aza-, and thiabicyclo[3.1.0] hexylphenyl oxazolidinones

A new class of oxazolidinone antibacterials incorporating oxygen-, nitrogen-, or sulfur-containing heterobicyclic C-rings is described. The in vitro potency and in vivo efficacy of these conformationally constrained oxazolidinone analogs are discussed.