777097-51-5

Upstream product

• 58655-59-7 2,2-dimethyl-N,N’-diphenylmalonic diamide 
• 62-53-3 aniline 
• 5659-93-8 2,2-Dimethylmalonyl chloride 

Downstream Products

• 1160040-22-1 (CH₃)2CC(NC₆H₅)N(C₆H₅)CNCH₂CH₂CH₃ 
• 1160040-18-5 (CH₃)2CC(NC₆H₅)N(C₆H₅)CNCH₂CH₂OCH₃ 
• 951770-80-2 PhN=C(CMe₂)(NPh)C=N(CH₂)2Cl 

Relevant academic research and scientific papers

Palladacyclic complexes bearing CNN-type ligands as catalysts in the Heck reaction

Preparations of novel unsymmetrical, tridentate nitrogen ligand precursors, PhN=C(CMe2)(NPh)C=N(CH2)2NMe2 (1) and PhN=C(CMe2)(NPh)C=N(CH2)Py (2), are described. Treatment of 1 with 1 molar equiv. (COD)PdCl2 in the presence of NEt3 or with 1 molar equiv. Pd(OAc)2 affords orthometallated palladium(II) complexes, [PhN=C(CMe2)-(N- η1-Ph)C=N(CH2)2NMe2]PdX (X = Cl (3); X = OAc (4)), respectively. Compound 3 can be yielded via the reaction of 4 with an excess of LiCl in methanol. Treatment of 2 with 1 molar equiv. of (COD)PdCl2, Pd(OAc)2 or Pd(TFA)2 affords orthometallated palladium(II) complexes, [PhN=C(CMe2)(N- η1-Ph)C=NCH2Py]PdX (X = Cl (5); X = OAc (6); X = TFA (7)), respectively. The crystal and molecular structures are reported for compounds 2, 3, 5 and 6. The application of these novel palladacyclic complexes to the Heck reaction with aryl halide substrates was examined.