77725-95-2

Upstream product

• 77729-07-8 (4-Benzyloxy-phenyl)-(7-chloro-quinazolin-4-yl)-amine 
• 2148-57-4 4,7-dichloroquinazoline 
• 31374-18-2 7-chloro-3,4-dihydroquinazolin-4-one 

Downstream Products

• 77726-00-2 4-(7-Chloro-quinazolin-4-ylamino)-2-pyrrolidin-1-ylmethyl-phenol 
• 77725-99-6 4-(7-Chloro-quinazolin-4-ylamino)-2-diethylaminomethyl-phenol 

Relevant academic research and scientific papers

Studies in Potential Filaricides: Part XI - Synthesis of 2-Dialkylaminomethyl-4-substitutedamino-phenols as Amodiaquine Analogs

A number of 4,7-disubstituted quinazolines (11-17) and 2-dialkylaminomethyl-4-acetylaminophenols (19-30) have been synthesized and tested for their antifilarial activity against Litosomoides carinii in cotton rat (Sigmodon hispidus).Of the compounds tested 19-21 and 26 cause 60percent fall in microfilarial count at a dose of 30 mg/kg given intraperitoneally daily for 6 days.None of the compounds possesses any macrofilaricidal activity.