77731-10-3 Usage
General Description
The chemical (5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester is a methyl ester derivative of cholic acid, a primary bile acid found in the human body. It is a steroid compound with a specific arrangement of hydroxyl groups and a double bond at the 5th and 2nd carbon positions. (5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester has been studied for its potential therapeutic properties, including its role in regulating cholesterol metabolism and its potential as a drug carrier for targeted delivery. Additionally, research has also shown that cholic acid and its derivatives may have anti-inflammatory and immunomodulatory effects, making them potential targets for the development of novel pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 77731-10-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,7,3 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77731-10:
(7*7)+(6*7)+(5*7)+(4*3)+(3*1)+(2*1)+(1*0)=143
143 % 10 = 3
So 77731-10-3 is a valid CAS Registry Number.
77731-10-3Relevant articles and documents
A mild one-pot method for conversion of various steroidal secondary alcohols into the corresponding olefins
Kumar, Raju Ranjith,Haveli, Shrutisagar Dattatraya,Kagan, Henri B.
experimental part, p. 1709 - 1712 (2011/09/14)
The addition of Tf2O to some hydroxy steroids in the presence of excess base directly leads to steroidal olefins. This methodology is useful for the one-pot synthesis of Δ2- or Δ3-steroids under mild conditions from the corresponding alcohols. Georg Thieme Verlag Stuttgart · New York.
Olefins of the cholane series from deoxycholic and cholic acids
Brieskorn,Mosandl
, p. 118 - 127 (2007/10/02)
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