77748-73-3Relevant academic research and scientific papers
New Strategy for Forging Contiguous Quaternary Carbon Centers via H 2 O 2 -Mediated Ring Contraction
Hu, Jiadong,Yu, Xin,Xie, Weiqing
, p. 2517 - 2524 (2017)
Stereospecific construction of contiguous quaternary carbon centers constitutes a major challenge in natural product synthesis. A general protocol that enables stereospecific construction of all stereoisomers of such a moiety remains elusive. In this article, we will discuss the oxidative ring contraction of all-substituted cyclic α-formyl ketones mediated by H 2 O 2, which provides a facile access to the stereospecific construction of contiguous quaternary carbon centers.
Stereochemical Studies. VIII. Further Studies of Stereochemical Effects on the Course of Oxidation of α-Acyloctahydronaphthalenones
Middleton, Sydney,Stock, Lionel E.
, p. 2467 - 2476 (2007/10/02)
trans-Fused octahydroindene-1- and -2-carboxylic acids are formed stereoselectively on oxidation of α-acyl derivatives of trans-fused octahydronaphthalen-1(2H)- and 2(1H)-ones by hydrogen peroxide.
