777850-76-7

Basic information

• Product Name: 3-Cyclopentene-1-carboxylicacid,2-amino-4-methyl-,(1R,2S)-(9CI)
• Synonyms: 3-Cyclopentene-1-carboxylicacid,2-amino-4-methyl-,(1R,2S)-(9CI)
• CAS NO: 777850-76-7
• Molecular Formula: C7H11NO2
• Molecular Weight: 0
• Product Categories: AMINOACID
• Mol File: 777850-76-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Cyclopentene-1-carboxylicacid,2-amino-4-methyl-,(1R,2S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclopentene-1-carboxylicacid,2-amino-4-methyl-,(1R,2S)-(9CI)(777850-76-7)
• EPA Substance Registry System: 3-Cyclopentene-1-carboxylicacid,2-amino-4-methyl-,(1R,2S)-(9CI)(777850-76-7)

Safety Data

• Hazardous Substances Data: 777850-76-7(Hazardous Substances Data)

Upstream product

• 139228-09-4 5-methylenetetrahydrocyclopenta[c]furan-1,3-dione 
• 939962-90-0 (-)-(1R,2R)-4-methyl-2-(3-phenyl-allyloxycarbonylamino)-cyclopent-4-enecarboxylic acid 3-phenyl-allyl ester 
• 198022-65-0 (-)-(1R,2S)-2-amino-4-methylenecyclopentanecarboxylic acid 

Relevant articles and documents

Quinine-mediated parallel kinetic resolution of racemic cyclic anhydride: stereoselective synthesis, relative and absolute configuration of novel alicyclic β-amino acids

Four endo-isomers of (1R,2S)-2-amino-4-methylenecyclopentanecarboxylic acid (+)-1 (Icofungipen) have been prepared in enantiomerically pure form. Three endo-isomers were obtained by quinine-mediated kinetic resolution of a racemic anhydride, followed by Curtius rearrangement. The fourth isomer was obtained by an exo-endo isomerization of (+)-1. The assignment of the absolute configuration is based either on the Cotton effect in the CD spectra or in correlation to already known structures.