777857-22-4

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 130812-44-1 N_α-phenylmethoxycarbonyl-D-tryptophan methyl ester 
• 501-53-1 benzyl chloroformate 
• 153-94-6 D-tryptophan 
• 2279-15-4 N-(benzyloxycarbonyl)-D-tryptophan 

Downstream Products

• 777857-23-5 (2R,3aS,8aS)-3a-phenylselenyl-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,2,8-tricarboxylic acid 1-benzyl ester 8-tert-butyl ester 2-methyl ester 
• 777857-27-9 3a-hydroxy-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 777857-25-7 3a-hydroxy-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,2,8-tricarboxylic acid 1-benzyl ester 8-tert-butyl ester 2-methyl ester 
• 777857-26-8 3a-phenylselanyl-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,2,8-tricarboxylic acid 1-benzyl ester 8-tert-butyl ester 2-methyl ester 
• 1001565-93-0 (2R,3aS,8aS)-3a-bromo-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,2,8-tricarboxylic acid 1-benzyl ester 8-tert-butyl ester 2-methyl ester 

Relevant academic research and scientific papers

A concise total synthesis of (+)-okaramine C

The first total synthesis of (+)-okaramine C is described. Our previously described selenocyclisation-oxidative deselenation sequence was used to establish a 3a-hydroxy-pyrrolo[2,3-b]-indole core, which was modified by selective epimerisation to the commo