777863-52-2Relevant academic research and scientific papers
Stereoselective synthesis of (2S, 8S)-2-benzyl hexahydro-pyrrodizin-3-one starting from (L)-proline based on stereoselective benzylation
Jing, Yi Jin,Ming, Hua Zheng,Wu, Xue,Guan, Rong Tian
, p. 3191 - 3196 (2007/10/03)
A pyrrolizidine alkaloid, (2S, 8S)-2-benzyl hexahydro-pyrrodizin-3-one, was synthesized from (L)-proline using diastereoselective benzylation as the key step. The absolute configuration of the target compound was confirmed through 2D H-H COSY and H-H NOES
