77791-00-5

Usage

Uses

Used in Solvent Applications:
TERT-BUTYL 2-NITROETHYL ETHER is used as a solvent for its ability to dissolve a wide range of substances, which is attributed to its high solvency. This makes it suitable for various industrial processes where a solvent with these characteristics is required.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, TERT-BUTYL 2-NITROETHYL ETHER is used as an intermediate in the synthesis of various organic compounds. Its role in the creation of pharmaceuticals is significant, as it aids in the production of a range of medicinal products.
Used in Organic Compound Synthesis:
Beyond pharmaceuticals, TERT-BUTYL 2-NITROETHYL ETHER is also utilized in the synthesis of other organic compounds. Its versatility in chemical reactions makes it a valuable component in the production of different organic substances across various industries.

Upstream product

• 625-48-9 2-nitro-1-ethanol 
• 115-11-7 isobutene 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 102219-65-8 α-xylo-3-t-butoxymethyl-5,6-O-isopropylidenetetrahydrofuro<2,3-d>isoxazole 
• 625-48-9 2-nitro-1-ethanol 

Relevant academic research and scientific papers

Unusual and unexpected reactivity of t-butyl dicarbonate (Boc2O) with alcohols in the presence of magnesium perchlorate. A new and general route to t-butyl ethers

(Chemical Equation Presented) A new mild method for protecting alcohols as t-butyl ethers is reported. The reaction proceeds with Mg(ClO4) 2 and Boc2O and shows general applicability. The deprotection of t-butyl ethers has also been revisited. Preliminary results indicate the CeCl3·7H2O/Nal system is a very suitable catalyst for their removal.

SYNTHESIS OF AMINO SUGARS VIA ISOXAZOLINES. DL- AND D-LIVIDOSAMINE (2-AMINO-2,3-DIDEOXY-RIBO-HEXOSE) DERIVATIVES FROM 4-VINYL-1,3-DIOXOLANES AND NITROACETALDEHYDE ACETALS

1,3-Dipolar cycloaddition of nitrile oxides, generated from nitroethanol and nitroacetaldehyde derivatives 3, 21 and 22, respectively, and of benzonitrile oxide to 4-vinyldioxolanes 1,2 gave ca 4:1 erythro/threo mixtures of corresponding isoxazolines.LAH reduction of erytho isoxazolines proceeded with similar (ca4:1) selectivity to furnish protected ribo-amino-polyols 11, 15, 19, DL- and D-lividosamines 31 and 33, respectively, as main products.The DL-lividosamine derivative 33 was obtained pure by crystallization.In the D-series, the corresponding ribo/arabino mixture D-31/D-32 was transformed to the known α-methyl D-lividosaminide D-37.