777939-36-3

Basic information

• Product Name: N-(5-(tert-butoxycarbonylamino)pentyl)-N-(benzyloxy)-2(E)-octenamide
• Synonyms: N-(5-(tert-butoxycarbonylamino)pentyl)-N-(benzyloxy)-2(E)-octenamide
• CAS NO: 777939-36-3
• Molecular Weight: 446.587
• Mol File: 777939-36-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(5-(tert-butoxycarbonylamino)pentyl)-N-(benzyloxy)-2(E)-octenamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-(tert-butoxycarbonylamino)pentyl)-N-(benzyloxy)-2(E)-octenamide(777939-36-3)
• EPA Substance Registry System: N-(5-(tert-butoxycarbonylamino)pentyl)-N-(benzyloxy)-2(E)-octenamide(777939-36-3)

Safety Data

• Hazardous Substances Data: 777939-36-3(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 51644-96-3 5-tert-butoxycarbonylamino-1-aminopentane 
• 462-94-2 1,5-diaminopentane 
• 100808-08-0 (E)-oct-2-enoic acid chloride 

Relevant articles and documents

Synthesis and biological evaluation of new acinetoferrin homologues for use as iron transport probes in mycobacteria

Four new acinetoferrin homologues were synthesized using a modular synthetic approach. Two linear and two cyclic imide derivatives were generated and evaluated for growth stimulating behavior in Mycobacterium avium subsp paratuberculosis. The yield for the tandem coupling of a functionalized aminohydroxamic acid motif (2 equiv) to a tert-butyl citrate derivative was significantly improved using DCC and N-hydroxysuccinimide. 1H NMR spectroscopy (CD3OD) provided a convenient method for monitoring the final imidization step in TFA using the doublet patterns between 2.5 and 3.06 ppm. New protocols demonstrated that only a 20% growth enhancement was observed with M. avium subsp. paratuberculosis using the imide of acinetoferrin. Last, a siderophore from Streptomyces pilosus, deferrioxamine B, was shown to cross-feed M. avium subsp. paratuberculosis with the same efficiency as the more costly, native chelator, mycobactin J.