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Usage

Uses

Used in Organic Synthesis:
(TRICHLOROMETHYL)PENTAFLUOROBENZENE is utilized as a versatile intermediate in organic synthesis for its ability to engage in multiple chemical reactions, contributing to the development of a range of chemical products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (TRICHLOROMETHYL)PENTAFLUOROBENZENE is used as a key intermediate in the synthesis of various pharmaceuticals. Its reactivity and structural features make it valuable in creating new medicinal compounds.
Used in Agrochemical Production:
Similarly, in agrochemicals, (TRICHLOROMETHYL)PENTAFLUOROBENZENE serves as an intermediate, playing a crucial role in the synthesis of substances used in agricultural applications to protect crops and enhance yields.
Used as a Solvent:
(TRICHLOROMETHYL)PENTAFLUOROBENZENE is also employed as a solvent in certain chemical processes, taking advantage of its solubility properties to facilitate reactions or dissolve substances.
Safety Note:
Given its potential hazards to human health and the environment, (TRICHLOROMETHYL)PENTAFLUOROBENZENE necessitates careful handling and storage with adherence to proper safety protocols.

InChI:InChI=1/C7Cl3F5/c8-7(9,10)1-2(11)4(13)6(15)5(14)3(1)12

Upstream product

• 56-23-5 tetrachloromethane 
• 363-72-4 Pentafluorobenzene 
• 434-64-0 perfluorotoluene 
• 771-56-2 2,3,4,5,6-pentafluorotoluene 

Downstream Products

• 58161-50-5 α-chloroheptafluorostyrene 
• 58161-57-2 1-((Z)-1,3-Dichloro-2,3,3-trifluoro-propenyl)-2,3,4,5,6-pentafluoro-benzene 
• 58161-58-3 1-((E)-1,3-Dichloro-2,3,3-trifluoro-propenyl)-2,3,4,5,6-pentafluoro-benzene 
• 344-07-0 1-chloro-2,3,4,5,6-pentafluorobenzene 
• 58161-51-6 α,α,β-trichloroperfluoroethylbenzene 
• 652-30-2 pentafluorobenzylidene chloride 
• 5122-04-3 α,β,β-trichloropentafluorostyrene 
• 137730-96-2 C₁₉ClF₁₅S₂ 
• 87228-30-6 p-Chloro-o,o,m,m-tetrafluorotrichloromethylbenzene 
• 128100-05-0 Bis(p-chlorotetrafluorophenyl)dichloromethane 
• 76071-75-5 benzoyl chloride perfluorophenylhydrazone 
• 112086-96-1 1,3,5-tris(pentafluorophenyl)-1,2,4-triazole 
• 112086-95-0 2,3,4,5,6-Pentafluoro-benzoic acid N'-[1-chloro-1-pentafluorophenyl-meth-(Z)-ylidene]-N-pentafluorophenyl-hydrazide 
• 112086-93-8 N,N'-bis-(pentafluorobenzoyl)pentafluorophenylhydrazine 

Relevant academic research and scientific papers

T -BuONa-mediated direct C-H halogenation of electron-deficient (hetero)arenes

An efficient halogenation of electron-deficient (hetero)arenes is described. The reaction utilizes common t-BuONa as a catalyst (for iodination) or a promoter (for bromination and chlorination), and perfluorobutyl iodide, CBr4 or CCl4 as the readily-available halogenating agents, respectively. The protocol features broad scope, high efficiency, mild conditions and gram scalability. An ionic pathway involving halogen bond formation and halophilic attack is proposed. The utility of the resulting iodinated heteroarenes is demonstrated in visible light-mediated Caryl-Caryl cross-coupling reaction.

PREPARATION OF POLYFLUOROBENZOTRIHALIDES BY THE REACTIONS OF OCTAFLUOROTOLUENE AND ITS DERIVATIVES WITH ALUMINUM HALIDES. SYNTHESIS OF POLYFLUOROSTILBENES AND DECAFLUOROTOLAN

Reactions of some polyfluoro aromatic compounds containing a CF3 group with aluminum halides (AlCl3, AlBr3) were studied.In these reactions there occurs the replacement of fluorine atoms by chlorine or bromine both in the side chain in aromatic ring.Treat

FORMATION OF POLYFLUOROTRICHLOROMETHYLBENZENES FROM PENTAFLUOROBENZENE AND CCl4 IN THE PRESENCE OF AlCl3

The reaction of pentafluorobenzene with CCl4 in the presence of AlCl3 gives p-chloro-o,o,m,m-tetrafluorotrichloromethylbenzene as the major product along with pentafluorotrichloromethylbenzene and bis(p-chlorotetrafluorophenyl)dichloromethane.