77825-92-4Relevant academic research and scientific papers
15-Oxygenated Sterols by m-Chloroperbenzoic Acid Oxidation of 3β-Acetoxy-5α-cholesta-8,14-diene
Anastasia, Mario,Allevi, Pietro,Fiecchi, Alberto,Scala, Antonio
, p. 3265 - 3267 (1981)
The epoxidation of 3β-acetoxy-5α-cholesta-8,14-diene with 1 molar equiv of m-chloroperbenzoic acid has been found useful for the synthesis of 15-oxygenated sterols.The major product of the reaction, 3β-acetoxy-14α,15α-epoxy-5α-cholest-8-ene, is decomposed on silica to a (1:1) mixture of 3β-acetoxy-5α-cholesta-8(14),9(11)-dien-15α-ol and 3β-acetoxy-5α-cholest-8(14)-ene-9α,15α-diol.The minor product obtained in the epoxidation is 3β-acetoxy-8α,9α-epoxy-5α-cholest-14-ene.
