77826-01-8Relevant academic research and scientific papers
Facile, High-Yield Synthesis of Spiro C-17 Steroidal Oxetan-3'-ones
Pons, Michel,Simons, S. Stoney
, p. 3262 - 3264 (1981)
The facile, high-yield conversion of C-17 α-keto mesylates of glucocorticoids to spiro C-17 oxetan-3'-ones is described.This reaction, involving treatment with strong base (KOH, NaOMe, or KO-t-Bu) in EtOH or THF, represents a major improvement for the pre
