77831-48-2Relevant articles and documents
Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives
Mente?e,Y?lmaz,Karaali,ülker,Kahveci
, p. 336 - 342 (2014/06/09)
This study presents a synthesis of new series of some benzimidazole, bisbenzimidazole and perimidine derivatives via microwave technique, which, leads to the good product yields and short reaction times. The structure of newly synthesized compounds was confirmed by 1H NMR and 13C NMR spectra. These compounds were screened for their lipase inhibition activity. Then, all compounds were evaluated with regard to pancreatic lipase activity, and some of the 2-substituted perimidines, bisperimidine and bisbenzimidazole derivatives showed lipase inhibition at various concentrations.
The Synthesis of 3- and 5-Amino-1,2,4-Oxadiazoles. A Caveat
Dimsdale, Michael J.
, p. 37 - 41 (2007/10/02)
Evidence obtained from a single series of compounds demonstrates the need for care when assigning structures to amino-1,2,4-oxadiazoles using the methodology described in the literature.Certain synthetic methods can give rise to different position isomers
