77831-51-7

Basic information

• Product Name: 2-(2,6-DICHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE
• Synonyms: 2-(2,6-DICHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE;BENZENEETHANIMIDAMIDE,2,6-DICHLORO-N-HYDROXY;(E)-2-(2,6-dichlorophenyl)-N'-hydroxyethanimidamide
• CAS NO: 77831-51-7
• Molecular Formula: C₈H₈Cl₂N₂O
• Molecular Weight: 219.07
• Mol File: 77831-51-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2,6-DICHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,6-DICHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE(77831-51-7)
• EPA Substance Registry System: 2-(2,6-DICHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE(77831-51-7)

Safety Data

• Hazardous Substances Data: 77831-51-7(Hazardous Substances Data)

Usage

Type of compound

N-hydroxyacetamidine derivative

Chlorine substituents

Two on the phenyl ring

Potential use

Antiparasitic drug

Specific treatment

African sleeping sickness caused by Trypanosoma brucei

Mechanism of action

Inhibitory effects on trypanothione reductase, an enzyme involved in protecting the parasite from oxidative damage

Current status

Being researched for potential use in treating parasitic diseases.

Upstream product

• 3215-64-3 2,6-dichlorophenylacetonitrile 

Downstream Products

• 77831-54-0 5-amino-3(2,6-dichlorobenzyl)-1,2,4-oxadiazole 
• 77831-53-9 5-trichloromethyl-3(2,6-dichlorobenzyl)-1,2,4-oxadiazole 
• 77831-52-8 O-methyl-2,6-dichlorophenylacetamidoxime 
• 77831-55-1 2,6-dichlorobenzyl cyanamide 

Relevant articles and documents

The Synthesis of 3- and 5-Amino-1,2,4-Oxadiazoles. A Caveat

Evidence obtained from a single series of compounds demonstrates the need for care when assigning structures to amino-1,2,4-oxadiazoles using the methodology described in the literature.Certain synthetic methods can give rise to different position isomers