77832-42-9

Upstream product

• 139107-32-7 C₉H₁₁BO₄ 
• 96189-00-3 (+/-)-4-acetoxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 
• 90428-87-8 (S)-4-acetoxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 
• 94412-95-0 (R)-2-methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl nitrate 
• 95413-30-2 (R)-2-methyl-4-oxo-3-(2-propynyl)-2-cyclopentenyl methanesulfonate 

Downstream Products

• 77087-34-4 (S)-4-hydroxy-3-methyl-2-(2-propynyl)-cyclopent-2-ene-1-one 
• 95413-30-2 (R)-2-methyl-4-oxo-3-(2-propynyl)-2-cyclopentenyl methanesulfonate 
• 90428-87-8 (S)-4-acetoxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 

Relevant academic research and scientific papers

Preparation of (4S)-4-hydroxy-3-methyl-2-(2′-propynyl)-2-cyclopentenone by combination of enzymatic hydrolysis and chemical transformation

(4S)-4-Hydroxy-3-methyl-2-(2′-propynyl)-2-cyclopentenone ((S)-2), which is an important alcohol moiety of optically active pyrethroid insecticides, was prepared from the corresponding racemic acetate ((±)-1) by the combination of enzymatic hydrolysis and chemical transformation in high chemical and optical yields.

PREPARATION OF OPTICALLY ACTIVE SECONDARY ALCOHOLS BY COMBINATION OF ENZYMATIC HYDROLYSIS AND CHEMICAL TRANSFORMATION

Several kinds of optically active secondary alcohols (S)-2, which are important intermediates of bioactive compounds, were prepared from the corresponding racemic acetate (+/-)-1 in high chemical and optical yields by combination of enzymatic hydrolysis and chemical transformation.