77837-30-0Relevant academic research and scientific papers
Synthesis of substituted N-hydroxyureas via the in situ generation of t-butoxy isocyanate
Krause, Josef G.,Leskiw, Brian D.,Emery, Michelle L.,McGahan, Megan E.,McCourt, Mary P.,Priefer, Ronny
body text, p. 3568 - 3570 (2010/08/07)
Treatment of primary and secondary amines with tert- butylmesitylenesulfonoxycarbamate and a base afforded tert-butoxyurea, which when treated with an acid ultimately yielded substituted N-hydroxyureas. It is proposed that this proceeded via the generation of t-butoxy isocyanate in situ. This method allows for the synthesis of both mono and disubstituted N-hydroxyureas.
